ABSTRACT
Neonatal hypoxic-ischemic encephalopathy (HIE) is a perinatal hypoxic ischemic injury caused by hypoxia, which is one of the common neurological disorders in neonatal period, and the untimely treatment can lead to serious complications and sequelae, including poor neurodevelopmental outcome and death.Currently, no specific therapeutic drugs have been found for this disease, so early clinical intervention is very important.This article reviews the advantages and disadvantages of cranial ultrasound, amplitude-integrated electroencephalography, and near-infrared spectroscopy for the diagnosis of neonatal HIE and the monitoring of brain function, as well as the outlook for the use of portable magnetic resonance.The aim is to provide cerebral function monitoring and early diagnosis and treatment for children with HIE, and to better predict their immediate and long-term outcomes.